General description
FRAT1 belongs to the GSK-3-binding protein family. It may function in tumor progression and in lymphomagenesis. It positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. It may play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.
Immunogen
FRAT1 (NP_005470, 104-138)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human FRAT1.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
This product has met the following criteria to qualify for the following awards: